Cost-Effectiveness of Carbon Ion Radiation Therapy for Skull Base Chordoma Utilizing Long-Term (10-Year) Outcome Data

Long -Term Outcome Therapy of Toxic Diffuse Goiter in Tehran

SUMMARY In order to evaluate the long-ter m effects of antithyroids and ahlative therapy on patients with toxic diffuse goiter (TDG) in an iodine deficient region, 206 patients were studied in Tehran. Hyperthyroidism recurred in 50%, of 80 patients treated with Methimazole (MMI), from one week to 48 months after cessation of therapy. Another 40 patients remained in remission. Of 102 patients t...

MRI characterization of skull base chordoma and chondrosarcoma in a patient collective referred for proton radiation therapy

MR Imaging Grading System for Skull Base Chordoma.

BACKGROUND AND PURPOSE Skull base chordoma has been widely studied in recent years, however, imaging characteristics of this tumor have not been well elaborated. The purpose of this study was to establish an MR imaging grading system for skull base chordoma. MATERIALS AND METHODS In this study, 156 patients with skull base chordomas were retrospectively assessed. Tumor-to-pons signal intensit...

Factors for tumor progression in patients with skull base chordoma

Skull base chordoma is a rare and fatal disease, recurrence of which is inevitable, albeit variable. We aimed to investigate the clinicopathologic features of disease progression, identify prognostic factors, and construct a nomogram for predicting progression in individual patients. Data of 229 patients with skull base chordoma treated by one institution between 2005 and 2014 were retrieved an...

Feasibility of proton beam therapy for chordoma and chondrosarcoma of the skull base.

We explored the general feasibility of proton beam therapy for chordoma and chondrosarcoma of the skull base. Clinical records and treatment-planning data of patients with the pathological diagnosis of chordoma or chondrosarcoma were examined. Proton beam therapy was administered for gross tumor mass as well as microscopic residual disease after surgery. The prescribed dose was determined to ma...